Salvatore Ferla Selected Research

fosbretabulin (combretastatin A4)

3/2021	A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
8/2020	Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
11/2019	Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.
1/2017	Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.

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Salvatore Ferla Research Topics

Disease

9	Neoplasms (Cancer) 06/2022 - 01/2017
5	Infections 08/2021 - 11/2019
3	Schistosomiasis (Bilharziasis) 12/2021 - 12/2018
3	Prostatic Neoplasms (Prostate Cancer) 10/2019 - 08/2016
1	Caliciviridae Infections 08/2021
1	Lung Injury 01/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Coronavirus Infections 01/2021
1	Blindness (Hysterical Blindness) 10/2020
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 10/2020
1	Respiratory Syncytial Virus Infections 01/2020
1	Neglected Diseases 11/2019
1	Dengue (Dengue Fever) 01/2019
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 11/2017
1	Constipation 04/2017
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 04/2017
1	Hypertension (High Blood Pressure) 01/2016
1	Hepatitis C 12/2015
1	Parkinsonian Disorders (Parkinsonism) 01/2012
1	Parkinson Disease (Parkinson's Disease) 01/2012

Drug/Important Bio-Agent (IBA)

5	TubulinIBA 06/2022 - 01/2017
4	Antiviral Agents (Antivirals)IBA 08/2021 - 01/2019
4	fosbretabulin (combretastatin A4)IBA 03/2021 - 01/2017
3	Praziquantel (Biltricide)FDA Link 12/2021 - 12/2018
2	Pharmaceutical PreparationsIBA 12/2021 - 01/2017
2	VaccinesIBA 08/2021 - 12/2019
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2021
2	enzalutamideIBA 10/2019 - 08/2016
2	bicalutamide (Casodex)FDA LinkGeneric 10/2019 - 08/2016
1	pyrimidineIBA 06/2022
1	Aniline CompoundsIBA 06/2022
1	PalladiumIBA 03/2021
1	PyrrolesIBA 03/2021
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2021
1	Serine Proteases (Serine Protease)IBA 01/2021
1	Receptor-Interacting Protein Serine-Threonine KinasesIBA 01/2021
1	Caspase 3 (Caspase-3)IBA 01/2021
1	LectinsIBA 01/2021
1	Monoclonal AntibodiesIBA 01/2021
1	Complement System Proteins (Complement)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	Rhodopsin (Visual Purple)IBA 10/2020
1	Phosphates (Orthophosphate)IBA 08/2020
1	Antineoplastic Agents (Antineoplastics)IBA 05/2020
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 05/2020
1	ThiazolesIBA 05/2020
1	pyridineIBA 04/2020
1	ThiophenesIBA 04/2020
1	Suramin (Suramin Sodium)IBA 01/2020
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	ostarineIBA 10/2019
1	Hydroxyeicosatetraenoic Acids (HETE)IBA 11/2017
1	Androgen Receptor AntagonistsIBA 07/2017
1	BenzamidesIBA 07/2017
1	plecanatideIBA 04/2017
1	uroguanylinIBA 04/2017
1	Guanylate Cyclase (Guanylyl Cyclase)IBA 04/2017
1	OxazolesIBA 01/2017
1	Antimitotic AgentsIBA 01/2017
1	hydroxide ionIBA 01/2016
1	Subgenomic RNAIBA 12/2015
1	EnzymesIBA 12/2015
1	SynucleinsIBA 01/2012

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 01/2021 - 12/2018
1	Castration 07/2017
1	Deep Brain Stimulation 01/2012